Failure of the veins to adequately circulate the blood, especially from the lower extremities.
- The typical signs of chronic venous insufficiency include pedal edema, varicose veins and skin hyperpigmentation.
- Europeans use OPCs to treat various vascular disorders, including varicose veins, venous insufficiency, capillary fragility, and retinopathies.
- Rigorous clinical investigation of Centella asiatica has been conducted on chronic venous insufficiency and varicose veins.
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