A cytotoxic compound of the alkaloid class obtained from the Madagascar periwinkle and used to treat acute leukemia and other cancers.
- Nitrofurantoin, dapsone, metronidazole, isoniazid, disulfiram, amiodarone, vincristine, cisplatin, Taxol, phenytoin, chloramphenicol, hydralazine, and high-dose pyridoxine can all lead to neuropathies.
- Digoxin, morphine, ephedrine, vincristine, ergotamine, bromocriptine, and others are carefully tested and standardized drugs from plants.
- The patient was treated per the hyper-CVAD protocol (cyclophosphamide, doxorubicin, vincristine, and dexamethasone) with intrathecal prophylaxis and achieved a complete remission.
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