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Tay–Sachs disease Line breaks: Tay–Sachs dis|ease
Pronunciation: /teɪˈsaks/

Definition of Tay–Sachs disease in English:


[mass noun]
An inherited metabolic disorder in which certain lipids accumulate in the brain, causing spasticity and death in childhood.
Example sentences
  • Tay-Sachs disease occurs when the body lacks hexosaminidase A, a protein that helps break down a chemical found in nerve tissue called gangliosides.


Early 20th century: from the names of Warren Tay (1843–1927), English ophthalmologist, and Bernard Sachs (1858–1944), American neurologist, who described it in 1881 and 1887 respectively.

Definition of Tay–Sachs disease in:
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