Definition of acetylcholinesterase in English:


Line breaks: acetyl|cholin|ester|ase
Pronunciation: /ˌasɪtʌɪlˌkəʊlɪnˈɛstəreɪz
, -tɪl-/


[mass noun] Biochemistry
  • An enzyme that causes rapid hydrolysis of acetylcholine. Its action serves to stop excitation of a nerve after transmission of an impulse.
    More example sentences
    • An early favorite target was the vital enzyme acetylcholinesterase, required for hydrolysis of acetylcholine at neuromuscular junctions, and it has been exploited by agrochemical companies in a spectacular manner.
    • Once released, ACh must be removed rapidly in order to allow repolarization to take place; this step, hydrolysis, is carried out by the enzyme, acetylcholinesterase.
    • All nerve agents act by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine.

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