An assumption about the form of an unknown function which is made in order to facilitate solution of an equation or other problem.
- The conventional ansatz for the B-state dominance in S65T is that the negative charge on the anionic Glu - 222 prevents wt-Cro ionization in the GS and conversely, the neutral Glu - 222 in the S65T mutant permits its permanent ionization.
- This observation is harder to rationalize within the conventional ansatz, that Thr - 203 rotates to form the HB to the anion only after ESPT.
- Using this approximation ansatz, several problems concerning planar rods reduce to elementary geometry, as seen from the following simple but illustrative examples.
1940s: from German Ansatz 'approach, attempt'.
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