- 1Cause (someone) to become hostile: the aim was to antagonize visiting supportersMore example sentences
arouse hostility in, alienate, set someone against someone else, estrange, disaffect; anger, annoy, provoke, vex, irritate, offend• informal aggravate, rile, needle, get someone's back up, make someone's hackles rise, rub up the wrong way, ruffle someone's feathers, rattle someone's cage, get up someone's nose, get in someone's hair, get someone's dander up, get under someone's skin
- Why go out of the way to offend and antagonize religious people?
- It is spending astronomical amounts of money, alienating allies and further antagonizing opponents.
- I fully admit I have gone out of my way on more than one occasion to needle and to antagonize him.
- 2 Biochemistry (Of a substance) act as an antagonist of (a substance or its action): two other drugs antagonized the antidepressant-like effectMore example sentences
- For example, oxytocin's calming effects are enhanced by estrogen, but antagonized by androgen, she notes.
- Another approach is using drugs to antagonise the peripheral effects of opioids so that bowel dysfunction is reversed, speeding discharge from hospital.
- They also found that ADHD children responded variably to different B vitamins, with pyridoxine and thiamine antagonizing each other's benefits.
mid 18th century (in the sense 'struggle against'): from Greek antagōnizesthai, from ant- 'against' + agōnizesthai 'struggle' (from agōn 'contest').