noun (plural autoantibodies)Physiology
An antibody produced by an organism in response to a constituent of its own tissues.
- Autoantibodies such as antinuclear antibodies and myositis-specific autoantibodies bind to proteins normally present inside one's own normal skin and muscle cells.
- Examples of these substances include plasma proteins such as albumin and immunoglobulins, pathogenic autoantibodies, clotting factors, endotoxins, and proinflammatory cytokines.
- All patients had significant increases in autoantibodies against neural antigens.
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