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autocrine Line breaks: auto|crine
Pronunciation: /ˈɔːtə(ʊ)krʌɪn/

Definition of autocrine in English:


Denoting or relating to a cell-produced substance that has an effect on the cell by which it is secreted.
Example sentences
  • We reasoned that if dopamine is also produced by the alveolar epithelial cells, then it may act as a paracrine or autocrine substance thus contributing to the regulation of lung liquid clearance.
  • The amount of ligand that has been released by the autocrine cell in response to the activation is insufficient in this case to sustain signaling.
  • In particular, spatially localized autocrine signaling may confer directional persistence to cell migration, as suggested by recent experimental observations.


1980s: from auto-1 + Greek krinein 'to separate'.

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