Definition of centromere in English:


Line breaks: centro|mere
Pronunciation: /ˈsɛntrə(ʊ)mɪə


  • The point on a chromosome by which it is attached to a spindle fibre during cell division.
    More example sentences
    • In fact, we did not find any informative marker in the three chromosomal divisions around the centromere of this chromosome.
    • The presence of a kinetochore spot indicates the centromere region of each chromosome.
    • We conclude that chromosomes with damaged centromeres fail to correctly attach to the spindle, thus producing MN and monosomy.



More example sentences
  • Strains were transformed with a control centromeric plasmid or a centromeric plasmid carrying the wild-type GUK1 gene.
  • In Drosophila, relocation of a euchromatic gene near centromeric or telomeric heterochromatin often leads to its mosaic silencing.
  • In addition, binding of the yeast CBF3 kinetochore complex to centromeric DNA was severely compromised in this mutant.


1920s: from Latin centrum (see centre) + Greek meros 'part'.

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