Definition of chalone in English:

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Pronunciation: /ˈkaləʊn/
Pronunciation: /ˈkeɪləʊn/


A substance secreted like a hormone but having the effect of inhibiting a physiological process.
Example sentences
  • A reaction based on chalones cannot explain the re-transformation of the tumour into normal skin cells.
  • In addition, European researchers provided evidence for endogenous growth inhibitory substances, called chalones, in glands and tissues.
  • Regression of generalized leukaemia in rat is induced by the granulocytic chalone.


Early 20th century: from Greek khalōn 'slackening', present participle of khalaein, on the pattern of hormone.

For editors and proofreaders

Line breaks: cha|lone

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