noun[mass noun] Biochemistry
An enzyme, especially acetylcholinesterase, which hydrolyses esters of choline.
- Cholinesterase inhibitors, which reduce cholinesterase - the enzyme that breaks down acetylcholine - are the only FDA-approved treatment for Alzheimer's.
- By inhibiting cholinesterase, more acetylcholine is available for normal memory-related and cognitive functioning.
- In someone with Alzheimer's, cholinesterase breaks down and destroys acetylcholine, the neurotransmitter chemical.
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