Definition of cofactor in English:


Line breaks: co|fac¦tor
Pronunciation: /ˈkəʊfaktə


  • 1A contributory cause of a disease.
    More example sentences
    • The causes are clearly different from risk factors, which are the diseases accompanying cofactors.
    • Anorectal infections are a potent cofactor for HIV transmission.
    • Counseling can be offered to all patients with HCV infection to modify or prevent the adverse effects of cofactors, such as alcohol consumption, on disease progression.
  • 2 Biochemistry A substance (other than the substrate) whose presence is essential for the activity of an enzyme.
    More example sentences
    • Thiamine pyrophosphate, the active form of vitamin B-1, is a key cofactor of the essential enzymes involved in carbon metabolism.
    • Copper is usually utilized in organisms as a cofactor in enzymes or electron transfer proteins that catalyze redox reactions or oxygen chemistry.
    • Modifications of proteins that depend upon vitamin C as a cofactor include proline and lysine hydroxylations.
  • 3 Mathematics The quantity obtained from a determinant or a square matrix by removal of the row and column containing a specified element.
    More example sentences
    • Now, if A belongs to M n, then its matrix of cofactors A’ also has integer entries.

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Pronunciation: ˌkɒlərəˈtjʊərə
elaborate ornamentation of a vocal melody