noun[mass noun] Genetics
The relationship between the linear sequence of nucleic acid bases in the DNA of the gene and the sequence of amino acids in the protein encoded by the DNA.
- Ironically, our studies establishing gene - protein colinearity were performed with an enzyme consisting of two polypeptides encoded by adjacent genes in E. coli.
- The order and colinearity of these genes seems not to be disrupted between the two species.
- However, temporal colinearity of Hox gene expression and compact Hox clusters have so far only been described in the cephalochordate, amphioxus, and in vertebrates, but not in Cnidaria, Lophotrochozoa, or Ecdysozoa.
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