A substance that prevents the freezing of tissues, or prevents damage to cells during freezing.
- Chemicals called cryoprotectants reduce ice formation but have toxic effects that introduce their own problems.
- It is currently believed that effective cryoprotectants for proteins or enzymes in solution are excluded from the immediate vicinity of these biological molecules.
- Diplolepis overwinter in a prepupal stage; they are freezing-intolerant and develop cryoprotectants that lower their supercooling points.
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