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decarboxylate Line breaks: de|carb|oxyl|ate
Pronunciation: /ˌdiːkɑːˈbɒksɪleɪt/

Definition of decarboxylate in English:


[with object] Chemistry
1Eliminate a carboxylic acid group from (an organic compound): heating at 100°C in dryness decarboxylates the proteins to yield glutamic acid
More example sentences
  • Coproporphyrinogen III is transported to the interior of the mitochondrion, where 2 propionate residues are decarboxylated, yielding vinyl substituents on the 2 pyrrole rings.
  • Thus, malate produced following PEP carboxylation is readily decarboxylated and the CO 2 released.
  • In this compartment, called the matrix, the pyruvic acid is decarboxylated to a two-carbon acetyl group, releasing a CO 2 molecule, and is enzymatically joined to Coenzyme A, a large carrier molecule.
1.1 [no object] Undergo the process of decarboxylation: unstable carbamic acid decarboxylates to yield the amine
More example sentences
  • After electron transfer the product decarboxylates resulting in a ketylbiradical III that has a life time of about 4 s, long enough to reduce oxygen to superoxide.


Pronunciation: /ˌdiːkɑːbɒksɪˈleɪʃ(ə)n/
Example sentences
  • The synthesis of serotonin is a two-step process involving a hydroxylation reaction catalyzed by the enzyme tryptophan - 5-monooxygenase and then a decarboxylation catalyzed by l-amino acid decarboxylase.
  • A major source of ammonium, especially in C 3 plants, arises in the mitochondria from the decarboxylation of glycine to serine by the glycine decarboxylase as part of the photorespiratory cycle.
  • Acetoacetate can undergo spontaneous decarboxylation to acetone, or be enzymatically converted to b-hydroxybutyrate through the action of b-hydroxybutyrate dehydrogenase.
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