Definition of demyelinate in English:


Line breaks: de|mye¦lin|ate
Pronunciation: /diːˈmʌɪəlɪneɪt


[with object] (usually as adjective demyelinating) Medicine
  • Cause the loss or destruction of myelin in (nerve tissue): a chronic demyelinating disease
    More example sentences
    • Multiple sclerosis is an inflammatory, autoimmune, demyelinating disease of the central nervous system.
    • About 50% of patients with a first demyelinating episode develop multiple sclerosis; interferon decreases this risk.
    • Currently, demyelinating diseases are permanent, and problems worsen as time goes on because there is no way to fix the underlying problem - restoring the myelin around the axons of brain cells.



Pronunciation: /-ˈneɪʃ(ə)n/
More example sentences
  • Recent work is again focused on the vascular changes as a basis of the breakdown of the blood-brain barrier that precedes the inflammation and demyelination in a multiple sclerosis plaque.
  • Postural hypotension has been associated with cerebral hypoperfusion and decreased oxygenation of the frontal lobes and with the presence of white matter lesions corresponding to demyelination and arteriosclerosis.
  • The lesions of demyelination are histopathologically characteristic of the disease.

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