Definition of derepress in English:

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derepress

Pronunciation: /ˌdiːrɪˈprɛs/

verb

[with object] Biochemistry & Genetics
Activate (enzymes, genes, etc.) from an inoperative or latent state.
Example sentences
  • About 3% of yeast genes are derepressed in tup1 mutants, as determined by microarray analysis.
  • In addition, these mutations were able to derepress endogenous genes at HML.
  • Starvation for histidine derepresses the entire operon, the longest then known.

Derivatives

derepression

noun
Example sentences
  • Indeed, guk1 and hpt1 mutants share several phenotypes (adenine derepression, purine excretion, and 8-azaguanine resistance).
  • The importance of the nucleosome in gene regulation is supported by the finding that mutations that alter intracellular levels of histones lead to transcriptional derepression of a variety of genes.
  • This model also predicts that deletion of the Set1 histone methyltransferase would lead to the derepression of subtelomeric genes.

For editors and proofreaders

Line breaks: de|re¦press

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