(abbreviation DDI or ddI)
noun[mass noun] Medicine
A drug which inhibits the replication of HIV and is used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analogue of a purine nucleoside.
- We have now extended these studies to investigate the induction of mutants and micronuclei in mice treated neonatally with ddI or ddI in combination with AZT.
- In January 2001 the Food and Drug Administration issued a special warning to pregnant women taking nucleoside analogues ddI and d4T after three women died.
- A much publicized case in point is that of didanosine or ddI, a key antiretroviral patented by the US-based drug transnational Bristol-Myers Squibb.
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