Definition of dideoxyinosine in English:

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Pronunciation: /ˌdʌɪdɪɒksɪˈɪnəʊsiːn/
(abbreviation DDI or ddI)


[mass noun] Medicine
A drug which inhibits the replication of HIV and is used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analogue of a purine nucleoside.
Example sentences
  • We have now extended these studies to investigate the induction of mutants and micronuclei in mice treated neonatally with ddI or ddI in combination with AZT.
  • In January 2001 the Food and Drug Administration issued a special warning to pregnant women taking nucleoside analogues ddI and d4T after three women died.
  • A much publicized case in point is that of didanosine or ddI, a key antiretroviral patented by the US-based drug transnational Bristol-Myers Squibb.


1970s: from di-1 'two' + deoxy- (in the sense 'that has lost oxygen') + inosine.

For editors and proofreaders

Line breaks: di|de¦oxy|ino¦sine

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