situated or moving in the direction in which a stream or river flows: [as adverb]:the bridge spanned the river just downstream of the rail line [as adjective]:deforestation could have disastrous consequences for downstream regions
Biology situated in or towards the part of a sequence of genetic material where transcription takes place later than at a given point:a termination signal was found downstream from the coding region
at a stage in the process of gas or oil extraction and production after the raw material is ready for refining.
downstream in other Oxford dictionaries
Definition of downstream in the US English dictionary