Either of two peptide compounds occurring naturally in the brain, related to the endorphins and having similar physiological effects.
- Within a few years, researchers had isolated two classes of peptide molecules, the enkephalins and the endorphins.
- Belief and expectation, cardinal components of hope, can block pain by releasing the brain's endorphins and enkephalins, thereby mimicking the effect of morphine.
- Endorphin and enkephalins are released, creating a euphoric effect.
1970s: from Greek enkephalos 'brain' (from en- 'in' + kephalē 'head') + -in1.
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