Share this entry

Share this page

fibrin

Line breaks: fi¦brin
Pronunciation: /ˈfʌɪbrɪn
 
, ˈfɪb-/

Definition of fibrin in English:

noun

[mass noun] Biochemistry
An insoluble protein formed from fibrinogen during the clotting of blood. It forms a fibrous mesh that impedes the flow of blood.
Example sentences
  • Plasminogen binds to both fibrinogen and fibrin, thereby being incorporated into a clot as it is formed.
  • In the assay, the addition of thrombin to citrated plasma causes the conversion of fibrinogen to fibrin, yielding a stops bleeding much quicker.
  • It converts fibrinogen to fibrin, and unlike thrombin, is unaffected by heparin.

Origin

early 19th century: from fibre + -in1.

Derivatives

fibrinoid

1
adjective
Example sentences
  • In addition, three patients had hyaline collagen degeneration, four myxoid degeneration, three fibrinoid degeneration, and six had mixed lesions.
  • Fibrin deposition was found in areas of fibrinoid necrosis within the glomeruli and in the interstitium.
  • Other nonspecific features include intimal proliferation, duplication and/or fragmentation of the internal elastic lamina, a sparse perivascular inflammatory infiltrate, and fibrinoid necrosis of the intima.

fibrinous

2
adjective
Example sentences
  • This progressive process involves alterations in fibrin turnover, which leads to the formation of fibrinous deposits and membranes with sequestration of infected fluid.
  • Upon review of the slides, we observed a fragment of bladder mucosa with dilated vascular spaces, hemorrhage, acute inflammation, fibrinous exudate, and focal fibrosis in the lamina propria.
  • Because the heart is constricted by fluid or a rigid fibrinous or calcified pericardium, negative intrathoracic pressure during inspiration is not transmitted to the pericardial sac.

Definition of fibrin in:

Share this entry

Share this page

 

What do you find interesting about this word or phrase?

Comments that don't adhere to our Community Guidelines may be moderated or removed.

Get more from Oxford Dictionaries

Subscribe to remove adverts and access premium resources

Word of the day tenebrous
Pronunciation: ˈtɛnɪbrəs
adjective
dark; shadowy or obscure