Definition of gene amplification in English:

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gene amplification

Pronunciation: /ˈjēn ˌampləfiˌkāSH(ə)n/

Entry from US English dictionary


The multiple replication of a section of the genome, which occurs during a single cell cycle and results in the production of many copies of a specific sequence of the DNA molecule.
Example sentences
  • The protein coded by these genes is accumulated to high levels by feeding larvae and gene amplification has not resulted in different discernible functions.
  • Over-expression of this gene is a result of gene amplification or translocation and has been detected in many human cancers.
  • Importantly, the technology eliminates the need for costly, time and labor intensive gene amplification or enzymatic interventions - two widespread methods currently used to perform such analyses.

For editors and proofreaders

Syllabification: gene am·pli·fi·ca·tion

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