Definition of I or he etc. will try anything once in English:

I (or he etc.) will try anything once

Used to indicate willingness to do or experience something new: Rosie was willing to try anything once
More example sentences
  • ‘I will try anything once,’ she declared, and proved it in her eighties by flying on Concorde, taking a trip in a helicopter and ascending in a hot air balloon.
  • I like everything, and I will try anything once, but for the most part I go for a simple style with clean lines.
  • While I haven't been exposed to a lot of exotic places or foods, I am just not a very picky eater and I will try anything once.
See parent entry: try

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Pronunciation: ɪnˈvɛnəm
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put poison on or into; make poisonous