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in silico Line breaks: in sil¦ico
Pronunciation: /ɪn ˈsɪlɪkəʊ/

Definition of in silico in English:

adjective& adverb

(Of scientific experiments or research) conducted or produced by means of computer modelling or computer simulation: [as adjective]: in silico analysis of the human genome [adverb]: students who are too squeamish to dissect a frog can perform the procedure in silico
More example sentences
  • This enables us to replicate cells in silico: we can simulate an increasing population of cells.
  • We examine the essence by reconstituting it in silico.
  • This in silico approach would be helpful in ranking textile dyes of the different classes based on their binding affinities.


1980s: Latin, literally 'in silicon' (with reference to the use of silicon chips in computer systems), on the pattern of in vitro and in vivo.

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