Definition of integrin in English:
Any of a class of animal transmembrane proteins involved in the adhesion of cells to each other and to their substrate.
- Transmembrane proteins, such as integrins, anchor cells to the substrate.
- Understanding the nature of the interaction between the integrin and cell adhesion molecules can aid in the design of potent therapeutics.
- The elucidation of the fly genome makes it relatively straightforward to generate and study mutations in proteins previously associated with integrins from other systems.
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