- 1The state of feeling annoyed, impatient, or slightly angry: much to my irritation, Chris fell asleepMore example sentences
- And all without the slightest signs of irritation or impatience.
- The impatience and irritation that was such a marked characteristic of New York is gone, replaced by a rare generosity and calm.
- Instead, his look of irritation and slight anger remained, making her quickly look back down to the paper.
- 1.1 [count noun] A thing that annoys or irritates someone: the minor irritations of lifeMore example sentences
irritant, source of irritation, source of vexation, annoyance, source of annoyance, thorn in someone's side/flesh, pinprick, pest, bother, trial, torment, plague, inconvenience, nuisance, bugbear, menaceNorth American • informal pain in the butt, nudnik, burr in/under someone's saddleAustralian/New Zealand • informal narkBritish • vulgar slang pain in the arse
- Naturally, this disability is attended by irritations, inconveniences, and some significant professional frustrations.
- The stress, irritations, fears and hopes are excised through simple repetitive movement.
- The entries cited in the catalogue deal with problems and irritations common to all portrait painters.
- 2Inflammation or other discomfort in a body part caused by reaction to an irritant substance: some chemicals cause a direct irritation to the skin leading to dermatitisMore example sentences
- Metaplastic changes are common lesions and occur in reaction to foreign substances or chronic irritation.
- Endoscopy allows doctors to check for irritation, ulcers, inflammation and abnormal tissue growth in the internal organs.
- Mosquito bites cause severe skin irritation through an allergic reaction to the insects' saliva.
- 2.1 Biology The stimulation of an organism, cell, or organ to produce an active response.More example sentences
- It has been shown that the mouse model has a predictive value for human responses to sensory irritation.
- Initially, cellular growth increases markedly in an effort to regenerate tissue in response to irritation.
late Middle English: from Latin irritatio(n-), from the verb irritare (see irritate).