Definition of isocratic in English:


Line breaks: iso|crat¦ic
Pronunciation: /ˌʌɪsə(ʊ)ˈkratɪk


(Of a chromatographic method) involving a mobile phase whose composition is kept constant and uniform.
More example sentences
  • Nitrate analysis was performed with an isocratic high-performance liquid chromatography method with UV-detection.
  • Because isocratic elution with the varied composition of the mobile phase gave unsatisfactory results, the gradient elution was applied.
  • The proteins were eluted by applying an isocratic flow of 40 ml buffer A followed by a linear gradient of 50% buffer B in 60 min.


early 19th century: from Greek isokratia 'equality of power' (from isos 'equal' + kratos 'strength') + -ic.

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