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leukotriene

Line breaks: leuko|tri¦ene
Pronunciation: /ˌluːkə(ʊ)ˈtrʌɪiːn
 
/

Definition of leukotriene in English:

noun

Biochemistry
Any of a group of biologically active compounds, originally isolated from leucocytes. They are metabolites of arachidonic acid, containing three conjugated double bonds.
Example sentences
  • Prostaglandins and leukotrienes from arachidonic acid metabolism are highly inflammatory molecules, and play an important role in the pathophysiology of asthma.
  • Arachidonic acid metabolites such as leukotrienes and thromboxanes have been shown to increase in the lung during ischemia-reperfusion injury in a dog model of warm ischemia.
  • In addition to chemokines, lipid metabolites such as leukotrienes and prostaglandins are emerging as important upstream controllers of DC migration toward LNs.

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