Definition of methotrexate in English:

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methotrexate

Pronunciation: /ˌmɛθəˈtrɛkseɪt/
/ˌmiːθəˈtrɛkseɪt/

noun

[mass noun] Medicine
A synthetic compound that interferes with cell growth and is used to treat leukaemia and other forms of cancer.
  • Chemical formula: C20H22N8O5
Example sentences
  • Cancer drugs used for primary bone cancer include methotrexate, doxorubicin, and cisplatin.
  • Treatment may include systemic steroids, intralesional steroid injection, antimalarials, or methotrexate.
  • Antimalarial drugs or immune response modifiers like methotrexate can reduce steroid dose and side effects.

Origin

1950s: from meth- (denoting a substance containing methyl groups) + elements of unknown origin.

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