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mismatch repair

Line breaks: mis|match re¦pair

Definition of mismatch repair in English:

noun

[mass noun]
A DNA repair system whereby one member of a mismatched pair of bases is converted to the normally matched base.
Example sentences
  • A nearest-neighbor bias around the mutated base pair suggests that mismatch repair counteracts alkylation damage.
  • This trend may be explained by variation in mutational tendencies or by biased mismatch repair after gene conversion events.
  • These effects were examined in an otherwise wild-type background and in combination with defects in DNA mismatch repair or specialized DNA polymerases.

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