Definition of mismatch repair in English:
A DNA repair system whereby one member of a mismatched pair of bases is converted to the normally matched base.
- A nearest-neighbor bias around the mutated base pair suggests that mismatch repair counteracts alkylation damage.
- This trend may be explained by variation in mutational tendencies or by biased mismatch repair after gene conversion events.
- These effects were examined in an otherwise wild-type background and in combination with defects in DNA mismatch repair or specialized DNA polymerases.
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