Share this entry

Share this page

mitogen

Line breaks: mito|gen
Pronunciation: /ˈmʌɪtədʒ(ə)n
 
/

Definition of mitogen in English:

noun

Physiology
A substance that induces or stimulates mitosis.
Example sentences
  • Platelet-derived growth factor is a major polypeptide growth factor found in human serum, platelets and fibroblasts and is a potent mitogen for cells of mesenchymal origin.
  • The technique of three-color flow cytometry was used to generate precise estimates of cytokine responses to cells collected from the blood, cultured and stimulated with a mitogen.
  • Cells from each individual were tested at 3 different concentrations of the mitogens for optimum stimulation.

Origin

1960s: from mitosis + -gen.

Derivatives

mitogenic

1
adjective
Example sentences
  • In addition, muscarinic receptor stimulation augmented the mitogenic responses of human airway smooth muscle cells to epidermal growth factor.
  • Endothelin - 1 has been implicated in pulmonary hypertension because of its dual vasoconstrictor and mitogenic actions.
  • When associated with vesicles of dipalmitoylphosphatidylcholine, surfactant protein C inhibited the mitogenic effect of lipopolysaccharide to a macrophage cell line.

Definition of mitogen in:

Share this entry

Share this page

 

What do you find interesting about this word or phrase?

Get more from Oxford Dictionaries

Subscribe to remove adverts and access premium resources

Word of the day prepotent
Pronunciation: prɪˈpəʊt(ə)nt
adjective
greater than others in power or influence