An embryonic cell from which nerve fibres originate.
- Neuroblastomas represent a spectrum of differentiation of primitive neuroblasts into mature ganglion cells.
- Only one cell of the cluster finally gives rise to a neuroblast because of lateral inhibition, involving the Notch receptor protein and its ligand Delta, which prevents other cells developing as neuroblasts.
- The esg gene is normally expressed in embryonic neuroblasts and contributes to central nervous system development.
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