noun[mass noun] Biochemistry
A vitamin of the B complex which is widely distributed in foods such as milk, wheat germ, and meat, and can be synthesized in the body from tryptophan. Its deficiency causes pellagra. Also called niacin.
- Alternative name: 3-pyridinecarboxylic acid; chemical formula: (C5H4N)COOH
- Thus, the enzymes nicotinic acid mononucleotide adenylyltransferase and NAD synthetase are essential for growth of E. coli (coded for by the genes nadD and nadE, respectively).
- Blood levels of pantothenic acid were significantly higher in CD patients, and there were no statistically significant differences in levels of vitamins B12 and C, nicotinic acid, and biotin.
- Because of its ability to cause large reductions in circulating levels of cholesterol, nicotinic acid is used to treat Type II, III, IV and V hyperlipoproteinemias.
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