Definition of nonsense mutation in English:

nonsense mutation

Line breaks: non|sense mu|ta¦tion

noun

Genetics
A mutation in which a sense codon that corresponds to one of the twenty amino acids specified by the genetic code is changed to a chain-terminating codon.
More example sentences
  • The proximity of the nonsense mutation to the start codon indicates that these mutations are null alleles.
  • Another mutant isolated from the screen, LPY727, contained a nonsense mutation at amino acid 15.
  • Another nonsense mutation at codon 187 is shared by the human, the chimpanzee and the gorilla, so that it is most likely to have occurred in their ancestral species.

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