Definition of osteoclast in English:

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Pronunciation: /ˈɒstɪə(ʊ)klast/


A large multinucleate bone cell which absorbs bone tissue during growth and healing.
Example sentences
  • The rate at which cells called osteoclasts break down bone is slowed, and the production of new bone increases.
  • Vitamin D indirectly stimulates osteoclasts to resorb bone and is necessary for the intestinal absorption of calcium.
  • Note the presence of numerous osteoclasts lining the bone trabeculae.



Example sentences
  • Bone mineral density is determined by the homeostasis between osteoblastic bone formation and osteoclastic bone resorption.
  • At the cellular level, there was decreased osteoblastic and increased osteoclastic activity.
  • There is usually scant osteoblastic or osteoclastic activity, and often there is a marrow component with fat or hematopoietic elements.


Late 19th century: from osteo- 'bone' + Greek klastēs 'breaker'.

For editors and proofreaders

Line breaks: osteo|clast

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