noun[mass noun] Genetics
The extent to which a particular gene or set of genes is expressed in the phenotypes of individuals carrying it, measured by the proportion of carriers showing the characteristic phenotype.
- Because of reduced penetrance, individuals of different genotypes can have the same phenotype.
- With the exception of the relatively rare high penetrance, single gene disorders, genetic tests differ little from most other medical tests, providing evidence of statistical risk only.
- High penetrance susceptibility genes probably account for no more than 5-10% of cases.
1930s: from German Penetranz.
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