Definition of penetrance in English:


Line breaks: pene|trance
Pronunciation: /ˈpɛnɪtr(ə)ns


[mass noun] Genetics
  • The extent to which a particular gene or set of genes is expressed in the phenotypes of individuals carrying it, measured by the proportion of carriers showing the characteristic phenotype.
    More example sentences
    • Because of reduced penetrance, individuals of different genotypes can have the same phenotype.
    • With the exception of the relatively rare high penetrance, single gene disorders, genetic tests differ little from most other medical tests, providing evidence of statistical risk only.
    • High penetrance susceptibility genes probably account for no more than 5-10% of cases.


1930s: from German Penetranz.

More definitions of penetrance

Definition of penetrance in:

Get more from Oxford Dictionaries

Subscribe to remove adverts and access premium resources

Word of the day maelstrom
Pronunciation: ˈmeɪlstrəm
a powerful whirlpool in the sea