Definition of penicillinase in English:

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Pronunciation: /ˌpɛnɪˈsɪlɪneɪz/


[mass noun] Biochemistry
An enzyme which can inactivate penicillin, produced by certain bacteria: the potential to produce penicillinase [count noun]: resistant to penicillinases
More example sentences
  • For example, the resistance to penicillin initially was due to production of an enzyme penicillinase by bacteria, antibiotics like cloxallin were developed which was resistant to penicillinase enzyme.
  • A control gene regulates the production of an enzyme that destroys the antibiotic, e.g. penicillinase which destroys penicillin.
  • Penicillin was first used in the early 1940s and by 1950, most Staphylococcus aureus organisms were resistant to the drug by virtue of elaboration of a penicillinase enzyme.

For editors and proofreaders

Line breaks: peni|cil¦lin|ase

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