Definition of phosphodiester bond in English:

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phosphodiester bond

Pronunciation: /ˌfɒsfə(ʊ)dʌɪˈɛstə/

noun

Biochemistry
A chemical bond of the kind joining successive sugar molecules in a polynucleotide.
Example sentences
  • DNA ligase and RNA ligase from the bacteriophage T4 catalyze the formation of the phosphodiester bond between two molecules of nucleic acid.
  • Ribozymes are molecules of ribonucleic acid that catalyze reactions on the phosphodiester bond of other RNAs.
  • Certain glycosylases also have abasic lyase activity, cleaving the phosphodiester bond adjacent to the abasic deoxyribose residue.

For editors and proofreaders

Line breaks: phospho|diester bond

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