Definition of procoagulant in English:

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procoagulant

Pronunciation: /ˌprəʊkəʊˈaɡjʊl(ə)nt/
Biochemistry

adjective

Relating to or denoting substances that promote the conversion in the blood of the inactive protein prothrombin to the clotting enzyme thrombin.
Example sentences
  • Protective mechanisms prevent thrombin and other procoagulant enzymes from forming in healthy intact blood vessels.
  • Thrombomodulin is an integral membrane glycoprotein that binds thrombin changing it from a procoagulant protein to an anticoagulant.
  • The cap acts as a protective barrier between circulating blood and the thrombogenic, procoagulant contents of the lesion.

noun

A procoagulant substance.
Example sentences
  • Taipan venom is overwhelmingly neurotoxic, including pre and post-synaptic neurotoxins, as well as powerful procoagulants and myolysins.
  • The exudate, procoagulants, and leukocytes form casts in the airways, resulting in poor gas exchange.
  • Chemotherapy acts by killing leukemic cells, which release procoagulants that can produce disseminated intravascular coagulation.

For editors and proofreaders

Line breaks: pro|coagu¦lant

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