Definition of proguanil in English:


Line breaks: pro|gua¦nil
Pronunciation: /prəʊˈɡwɑːnɪl


[mass noun] Medicine
A bitter-tasting synthetic compound derived from biguanide, used in the prevention and treatment of malaria.
More example sentences
  • Mefloquine is not standard treatment internationally, although alternative drugs such as atovaquone with proguanil or artemether with lumefantrine may help to manage uncomplicated malaria in an ambulatory setting.
  • They had taken chloroquine weekly and proguanil daily for chemoprophylaxis against malaria.
  • Another study comparing four prophylactic regimens in civilian travelers found that overall tolerability was the same among mefloquine, doxycycline, chloroquine plus proguanil, and atovaquone plus proguanil.


1940s: from pro(pyl) + (bi)guan(ide) (a crystalline base) + -il.

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