1Extend the duration of: an idea which prolonged the life of the engine by many years
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- The addition of a vasoconstrictor, such as epinephrine, constricts blood vessels and reduces vascular uptake, which further prolongs the duration of the anesthetic.
- The latter is known to be due to the fact that hypocalcemia prolongs the duration of phase two of the action potential of cardiac muscle.
- Hypothermia impairs the metabolism of drugs, prolonging the duration of some pharmacologic effects.
late Middle English: from Old French prolonguer, from late Latin prolongare, from pro- 'forward, onward' + longus 'long'.
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- Birth-related outcomes that were evaluated included estimated gestational age, length of prolongation, and delivery at term.
- Health has become the over-riding contemporary virtue, and the measure of health care in rich countries has become, to a great extent, the simple prolongation of life.
- The prognosis will be much improved if the reason for its continual exacerbation and consequent prolongation were removed.