noun[mass noun] Biochemistry
A protein present in blood plasma which is converted into active thrombin during coagulation.
- Contact with tissue factor triggers the coagulation cascade, resulting in the conversion of prothrombin to active thrombin.
- This complex activates prothrombin to thrombin in the presence of calcium ions.
- Years ago we said fibrinogen (a soluble protein) becomes a clot of insoluble fibrin by the action of thrombin made from soluble prothrombin in the presence of calcium.
For editors and proofreaders
Line breaks: pro|throm¦bin
Definition of prothrombin in:
What do you find interesting about this word or phrase?
Comments that don't adhere to our Community Guidelines may be moderated or removed.