Definition of replicase in English:


Line breaks: rep¦lic|ase
Pronunciation: /ˈrɛplɪkeɪz


[mass noun] Biochemistry
  • An enzyme which catalyses the synthesis of a complementary RNA molecule using an RNA template.
    More example sentences
    • Q-beta replicase based gene amplification: This approach involves production of RNA in the amplification reaction using QB replicase as the enzyme and reaction at fixed temperature.
    • The estimate is based on a large mutational target, the 804-base TMV MP gene that encodes the viral movement protein, which is a cognate sequence for the viral replicase.
    • As a replicase, Pol is highly sensitive to template defects and misinserts nucleotides only extremely rarely.


1960s: from the verb replicate + -ase.

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