Definition of take up the running in English:
Take over as pacesetter in a race.
- Meanwhile, White was starting to lose ground as Tootell and Purdie took up the running at the front of the race.
- Distinction, the 11-4 favourite, takes up the running with about half a mile to go and soon has the field strung out.
- The seven-year-old was always in the lead group and took up the running at Aintree when Ardent Scout unseated his rider at the ninth of the 22 fences.
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