Definition of transactivation in English:

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Pronunciation: /ˌtransaktɪˈveɪʃ(ə)n/
Pronunciation: /ˌtrɑːns-/ Pronunciation: /-nz-/


[mass noun] Biochemistry
Activation of a gene at one locus by the presence of a particular gene at another locus, typically following infection by a virus.
Example sentences
  • The timing of these events is complex and it should be noted that the transactivation of stress-inducible genes is not fully understood even in model systems.
  • These injurious substances have been reported to activate EGFR through direct ligand-mediated activation, or via transactivation.
  • In mouse pituitary gonadotrope cells, MMP2 and MMP9 can mediate EGFR transactivation.

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Line breaks: trans|ac¦ti¦va¦tion

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