Definition of transactivation in English:


Line breaks: trans|ac¦ti¦va¦tion
Pronunciation: /ˌtransaktɪˈveɪʃ(ə)n
, ˌtrɑːns-, -nz-/


[mass noun] Biochemistry
Activation of a gene at one locus by the presence of a particular gene at another locus, typically following infection by a virus.
More example sentences
  • The timing of these events is complex and it should be noted that the transactivation of stress-inducible genes is not fully understood even in model systems.
  • These injurious substances have been reported to activate EGFR through direct ligand-mediated activation, or via transactivation.
  • In mouse pituitary gonadotrope cells, MMP2 and MMP9 can mediate EGFR transactivation.

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Word of the day anomalous
Pronunciation: əˈnɒm(ə)ləs
deviating from what is standard, normal, or expected