Share this entry

Share this page

voltage clamp

Line breaks: volt|age clamp
Physiology

Definition of voltage clamp in English:

noun

A constant electrical potential applied to a cell membrane, typically in order to measure ionic currents.
Example sentences
  • The easiest method of measuring charge transfer across the membrane is the whole-cell voltage clamp because all motor charges in the cell contribute to the signal, making the signal large.
  • Under voltage clamp, we measured the membrane current of isolated photoreceptors with tight-seal electrodes in the whole-cell mode.
  • The lack of expression for a mutant was defined as no currents in a two-electrode voltage clamp from at least three different RNA injections and at least two different clones.

verb

Back to top  
(voltage-clamp) [with object] Apply a voltage clamp to (a membrane, cell, etc.): oocytes were voltage-clamped at −80 to −100 mV
More example sentences
  • Second, we have designed the circuit to remove series resistance error in voltage-clamping the cell.
  • The cells were voltage-clamped and perfused with an artificial intracellular solution containing 15 mM EGTA to ensure that the bulk of the Ca 2 + mobilized by depolarization is bound to this extrinsic buffer.
  • We cannot experimentally distinguish between this model and the one shown in Fig.8 because this would require performing tracer-flux experiments from a single voltage-clamped cell.

Definition of voltage clamp in:

Share this entry

Share this page

 

What do you find interesting about this word or phrase?

Comments that don't adhere to our Community Guidelines may be moderated or removed.

Get more from Oxford Dictionaries

Subscribe to remove adverts and access premium resources

Word of the day emulous
Pronunciation: ˈɛmjʊləs
adjective
seeking to emulate someone or something