Definición de dedifferentiate en inglés:

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dedifferentiate

Pronunciación: /ˌdiːdɪfəˈrɛnʃɪeɪt/

verbo

[no object] Biology
(Of a cell or tissue) undergo a reversal of differentiation and lose specialized characteristics: some types of human cells dedifferentiate in culture, becoming primitive, unspecialized cells
Más ejemplos en oraciones
  • For example, they found that the proliferating cells dedifferentiated, meaning they temporarily lost the characteristics of mature heart muscle cells and reverted to a more fetal type of proliferating cell.
  • By manipulating niche signals, they could make the stem cells differentiate, then dedifferentiate again.
  • The search for compounds to differentiate and dedifferentiate (specialize and despecialize) stem cells is accelerating due to advances in biotechnology for growing and screening cells.

Derivados

dedifferentiation

sustantivo
Oraciones de ejemplo
  • This probably reflects the presence of stem cells in the nail bud rather than cell dedifferentiation.
  • Our case could be an example of such a dedifferentiation.
  • In the presented tumor, there was no indication for dedifferentiation.
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