An introduced gene that causes a tumor cell to produce an enzyme that will attract a drug lethal to the tumor.
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- These mutant sperm would then be more likely to reach an egg, and as a result the mutant suicide gene would become more common.
- Typically, these studies have tested the use of the suicide gene from the herpes simplex virus to develop a gene therapy approach that kills cancer cells in the presence of the antiviral drug - gancyclovir.
- The polymers, which are both pH and temperature sensitive, may also function someday as ‘suicide genes’ for cancer cells, forcing the damaged cells to self-destruct, Mallapragada said.