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orphan British & World English

A child whose parents are dead

orphan drug British & World English

A synthetic pharmaceutical which remains commercially undeveloped

orphan assets British & World English

Funds accrued by an insurance company which belong to no specific or traceable investor, frequently deriving from underpayment of with-profit bonuses.

orphan virus British & World English

A virus that is not known to cause disease.

Orphan's court British & World English

(Formerly in England, and now in some states of the U.S.) a probate court having jurisdiction over the estate and persons of orphans.

little Orphan Annie British & World English

(A name for) a poor, deprived, or pathetic-looking girl or woman (originally, one who is an orphan).