Definition of -cule in English:

-cule

Syllabification: -cule

suffix

Forming nouns such as molecule, reticule, which were originally diminutives.

Origin

from French -cule or Latin -culus, -cula, -culum.

Definition of -cule in:

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Word of the day apposite
Pronunciation: ˈapəzit
adjective
apt in the circumstances or relation to something